sk mel 103 cells Search Results


ras mutant cancer cell lines  (ATCC)
97
ATCC ras mutant cancer cell lines
BAY 11-7082 treatment alters the expression of multiple genes <t>in</t> <t>NRAS,</t> KRAS, and HRAS mutant cancer cells. (A) Heatmaps showing the top 50 upregulated or downregulated genes in SKMEL-103, <t>AsPC1,</t> and RH-36 cells upon treatment with BAY 11-7082 (5 µM) for 48 h as compared with DMSO-treated cells. (B) Volcano plot showing top 15 genes upregulated or downregulated after 48-h treatment with BAY 11-7082 (5 µM) in <t>RAS</t> mutant cells
Ras Mutant Cancer Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sk+mel+103+cells/pmc11233160-157-0-16?v=ATCC
Average 97 stars, based on 1 article reviews
ras mutant cancer cell lines - by Bioz Stars, 2026-07
97/100 stars
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melanoma  (ATCC)
95
ATCC melanoma
BAY 11-7082 treatment alters the expression of multiple genes <t>in</t> <t>NRAS,</t> KRAS, and HRAS mutant cancer cells. (A) Heatmaps showing the top 50 upregulated or downregulated genes in SKMEL-103, <t>AsPC1,</t> and RH-36 cells upon treatment with BAY 11-7082 (5 µM) for 48 h as compared with DMSO-treated cells. (B) Volcano plot showing top 15 genes upregulated or downregulated after 48-h treatment with BAY 11-7082 (5 µM) in <t>RAS</t> mutant cells
Melanoma, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sk+mel+103+cells/us11896606-278-18-69?v=ATCC
Average 95 stars, based on 1 article reviews
melanoma - by Bioz Stars, 2026-07
95/100 stars
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senescent sk mel 103 cells  (Thermo Fisher)
99
Thermo Fisher senescent sk mel 103 cells
BAY 11-7082 treatment alters the expression of multiple genes <t>in</t> <t>NRAS,</t> KRAS, and HRAS mutant cancer cells. (A) Heatmaps showing the top 50 upregulated or downregulated genes in SKMEL-103, <t>AsPC1,</t> and RH-36 cells upon treatment with BAY 11-7082 (5 µM) for 48 h as compared with DMSO-treated cells. (B) Volcano plot showing top 15 genes upregulated or downregulated after 48-h treatment with BAY 11-7082 (5 µM) in <t>RAS</t> mutant cells
Senescent Sk Mel 103 Cells, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sk+mel+103+cells/pm40494025-320-9-18?v=Thermo+Fisher
Average 99 stars, based on 1 article reviews
senescent sk mel 103 cells - by Bioz Stars, 2026-07
99/100 stars
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human metastatic melanoma cell lines  (ATCC)
88
ATCC human metastatic melanoma cell lines
BAY 11-7082 treatment alters the expression of multiple genes <t>in</t> <t>NRAS,</t> KRAS, and HRAS mutant cancer cells. (A) Heatmaps showing the top 50 upregulated or downregulated genes in SKMEL-103, <t>AsPC1,</t> and RH-36 cells upon treatment with BAY 11-7082 (5 µM) for 48 h as compared with DMSO-treated cells. (B) Volcano plot showing top 15 genes upregulated or downregulated after 48-h treatment with BAY 11-7082 (5 µM) in <t>RAS</t> mutant cells
Human Metastatic Melanoma Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 88/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sk+mel+103+cells/us08252760-640-51-68?v=ATCC
Average 88 stars, based on 1 article reviews
human metastatic melanoma cell lines - by Bioz Stars, 2026-07
88/100 stars
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cdk4/6 inhibitor palbociclib  (Absource Diagnostics GmbH)
90
Absource Diagnostics GmbH cdk4/6 inhibitor palbociclib
BAY 11-7082 treatment alters the expression of multiple genes <t>in</t> <t>NRAS,</t> KRAS, and HRAS mutant cancer cells. (A) Heatmaps showing the top 50 upregulated or downregulated genes in SKMEL-103, <t>AsPC1,</t> and RH-36 cells upon treatment with BAY 11-7082 (5 µM) for 48 h as compared with DMSO-treated cells. (B) Volcano plot showing top 15 genes upregulated or downregulated after 48-h treatment with BAY 11-7082 (5 µM) in <t>RAS</t> mutant cells
Cdk4/6 Inhibitor Palbociclib, supplied by Absource Diagnostics GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sk+mel+103+cells/bio_rxiv__2024__01__26__577389-237-24-42?v=Absource+Diagnostics+GmbH
Average 90 stars, based on 1 article reviews
cdk4/6 inhibitor palbociclib - by Bioz Stars, 2026-07
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cell lines sk mel 28  (ATCC)
99
ATCC cell lines sk mel 28
BAY 11-7082 treatment alters the expression of multiple genes <t>in</t> <t>NRAS,</t> KRAS, and HRAS mutant cancer cells. (A) Heatmaps showing the top 50 upregulated or downregulated genes in SKMEL-103, <t>AsPC1,</t> and RH-36 cells upon treatment with BAY 11-7082 (5 µM) for 48 h as compared with DMSO-treated cells. (B) Volcano plot showing top 15 genes upregulated or downregulated after 48-h treatment with BAY 11-7082 (5 µM) in <t>RAS</t> mutant cells
Cell Lines Sk Mel 28, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sk+mel+103+cells/pmc01570143-140-10-15?v=ATCC
Average 99 stars, based on 1 article reviews
cell lines sk mel 28 - by Bioz Stars, 2026-07
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sk mel  (ATCC)
95
ATCC sk mel
BAY 11-7082 treatment alters the expression of multiple genes <t>in</t> <t>NRAS,</t> KRAS, and HRAS mutant cancer cells. (A) Heatmaps showing the top 50 upregulated or downregulated genes in SKMEL-103, <t>AsPC1,</t> and RH-36 cells upon treatment with BAY 11-7082 (5 µM) for 48 h as compared with DMSO-treated cells. (B) Volcano plot showing top 15 genes upregulated or downregulated after 48-h treatment with BAY 11-7082 (5 µM) in <t>RAS</t> mutant cells
Sk Mel, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sk+mel+103+cells/pmc10402251-36-7-12?v=ATCC
Average 95 stars, based on 1 article reviews
sk mel - by Bioz Stars, 2026-07
95/100 stars
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sk-mel-103  (Huntsman International LLC)
90
Huntsman International LLC sk-mel-103
BAY 11-7082 treatment alters the expression of multiple genes <t>in</t> <t>NRAS,</t> KRAS, and HRAS mutant cancer cells. (A) Heatmaps showing the top 50 upregulated or downregulated genes in SKMEL-103, <t>AsPC1,</t> and RH-36 cells upon treatment with BAY 11-7082 (5 µM) for 48 h as compared with DMSO-treated cells. (B) Volcano plot showing top 15 genes upregulated or downregulated after 48-h treatment with BAY 11-7082 (5 µM) in <t>RAS</t> mutant cells
Sk Mel 103, supplied by Huntsman International LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sk+mel+103+cells/10__1158_slash_0008___5472__can___18___3026-60-2-14?v=Huntsman+International+LLC
Average 90 stars, based on 1 article reviews
sk-mel-103 - by Bioz Stars, 2026-07
90/100 stars
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human melanoma cell lines  (ATCC)
96
ATCC human melanoma cell lines
BAY 11-7082 treatment alters the expression of multiple genes <t>in</t> <t>NRAS,</t> KRAS, and HRAS mutant cancer cells. (A) Heatmaps showing the top 50 upregulated or downregulated genes in SKMEL-103, <t>AsPC1,</t> and RH-36 cells upon treatment with BAY 11-7082 (5 µM) for 48 h as compared with DMSO-treated cells. (B) Volcano plot showing top 15 genes upregulated or downregulated after 48-h treatment with BAY 11-7082 (5 µM) in <t>RAS</t> mutant cells
Human Melanoma Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sk+mel+103+cells/pm37444518-40-1-13?v=ATCC
Average 96 stars, based on 1 article reviews
human melanoma cell lines - by Bioz Stars, 2026-07
96/100 stars
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sk mel 5  (ATCC)
96
ATCC sk mel 5
BAY 11-7082 treatment alters the expression of multiple genes <t>in</t> <t>NRAS,</t> KRAS, and HRAS mutant cancer cells. (A) Heatmaps showing the top 50 upregulated or downregulated genes in SKMEL-103, <t>AsPC1,</t> and RH-36 cells upon treatment with BAY 11-7082 (5 µM) for 48 h as compared with DMSO-treated cells. (B) Volcano plot showing top 15 genes upregulated or downregulated after 48-h treatment with BAY 11-7082 (5 µM) in <t>RAS</t> mutant cells
Sk Mel 5, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sk+mel+103+cells/pmc07224336-338-25-32?v=ATCC
Average 96 stars, based on 1 article reviews
sk mel 5 - by Bioz Stars, 2026-07
96/100 stars
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melanoma cell lines  (ATCC)
99
ATCC melanoma cell lines
BAY 11-7082 treatment alters the expression of multiple genes <t>in</t> <t>NRAS,</t> KRAS, and HRAS mutant cancer cells. (A) Heatmaps showing the top 50 upregulated or downregulated genes in SKMEL-103, <t>AsPC1,</t> and RH-36 cells upon treatment with BAY 11-7082 (5 µM) for 48 h as compared with DMSO-treated cells. (B) Volcano plot showing top 15 genes upregulated or downregulated after 48-h treatment with BAY 11-7082 (5 µM) in <t>RAS</t> mutant cells
Melanoma Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sk+mel+103+cells/10__1096_slash_fj__202302040r-32-17-32?v=ATCC
Average 99 stars, based on 1 article reviews
melanoma cell lines - by Bioz Stars, 2026-07
99/100 stars
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Image Search Results


BAY 11-7082 treatment alters the expression of multiple genes in NRAS, KRAS, and HRAS mutant cancer cells. (A) Heatmaps showing the top 50 upregulated or downregulated genes in SKMEL-103, AsPC1, and RH-36 cells upon treatment with BAY 11-7082 (5 µM) for 48 h as compared with DMSO-treated cells. (B) Volcano plot showing top 15 genes upregulated or downregulated after 48-h treatment with BAY 11-7082 (5 µM) in RAS mutant cells

Journal: Journal of Translational Medicine

Article Title: IκBα kinase inhibitor BAY 11-7082 promotes anti-tumor effect in RAS-driven cancers

doi: 10.1186/s12967-024-05384-4

Figure Lengend Snippet: BAY 11-7082 treatment alters the expression of multiple genes in NRAS, KRAS, and HRAS mutant cancer cells. (A) Heatmaps showing the top 50 upregulated or downregulated genes in SKMEL-103, AsPC1, and RH-36 cells upon treatment with BAY 11-7082 (5 µM) for 48 h as compared with DMSO-treated cells. (B) Volcano plot showing top 15 genes upregulated or downregulated after 48-h treatment with BAY 11-7082 (5 µM) in RAS mutant cells

Article Snippet: RAS mutant cancer cell lines (NRAS: M245, SKMEL-103, SKMEL-2; KRAS: PANC1, AsPC1, SU.86.86) were purchased from American Type Culture Collection (ATCC) as listed in Supplementary Tables and maintained in a humidified atmosphere of 5% CO2 at 37 °C in Dulbecco’s modified Eagle medium (Life Technologies, Carlsbad, CA, USA) or Roswell Park Memorial Institute-1640 Medium (Life Technologies), each supplemented with 10% fetal bovine serum and 1% penicillin/streptomycin (both from Life Technologies).

Techniques: Expressing, Mutagenesis

Model showing the new IκBα kinase Inhibitor BAY 11-7082 for Treating RAS-driven cancers. A model depicting various cancer types driven by oncogenic NRAS, KRAS, and HRAS mutations overexpress IκBα kinase. IκBα kinase can be effectively targeted by small molecule inhibitor BAY 11-7082, leading to downregulation of several prooncogenic signaling pathways, including PI3K-AKT signaling cascade and upregulation of apoptosis that contributes to tumor growth inhibition observed in RAS-driven cancers

Journal: Journal of Translational Medicine

Article Title: IκBα kinase inhibitor BAY 11-7082 promotes anti-tumor effect in RAS-driven cancers

doi: 10.1186/s12967-024-05384-4

Figure Lengend Snippet: Model showing the new IκBα kinase Inhibitor BAY 11-7082 for Treating RAS-driven cancers. A model depicting various cancer types driven by oncogenic NRAS, KRAS, and HRAS mutations overexpress IκBα kinase. IκBα kinase can be effectively targeted by small molecule inhibitor BAY 11-7082, leading to downregulation of several prooncogenic signaling pathways, including PI3K-AKT signaling cascade and upregulation of apoptosis that contributes to tumor growth inhibition observed in RAS-driven cancers

Article Snippet: RAS mutant cancer cell lines (NRAS: M245, SKMEL-103, SKMEL-2; KRAS: PANC1, AsPC1, SU.86.86) were purchased from American Type Culture Collection (ATCC) as listed in Supplementary Tables and maintained in a humidified atmosphere of 5% CO2 at 37 °C in Dulbecco’s modified Eagle medium (Life Technologies, Carlsbad, CA, USA) or Roswell Park Memorial Institute-1640 Medium (Life Technologies), each supplemented with 10% fetal bovine serum and 1% penicillin/streptomycin (both from Life Technologies).

Techniques: Protein-Protein interactions, Inhibition